The research
What's in every strip, and why it's there
Every DOSIS mood is built from ingredients that have been studied for years. Here's what each one does, how strong the research is, and where to read it yourself.
EXPLORE THE RESEARCHWhy a strip
The format pharmacies already trust
Oral thin films (dissolvable strips) are an established way to deliver active ingredients. They're used for medicines that need to be easy to take: no water, nothing to swallow, and a pre-measured dose in every strip.
For a daily supplement, that matters most for one reason: you actually take it. A tin in your bag beats a bottle in a cabinet.
Ingredient by ingredient
Mood by mood
Evidence ratings: ★★★ strong, ★★☆ studied in people, research growing. We'd rather show you the real picture than overpromise.
Caffeine from green tea
50 mgThe world's most studied stimulant. 50 mg is about half a cup of coffee: enough for a lift, without the big dose.
L-Theanine
30 mgAn amino acid found naturally in tea. It's often paired with caffeine, and studies of the pair look at attention and alertness.
Research
Good to know: most studies used more L-theanine than our 30 mg, usually 50 to 250 mg.
Vitamin B12
1000 mcgAn essential vitamin your body uses to turn food into energy and to make red blood cells. We use methylcobalamin, an active form.
Lion's Mane
30 mgA culinary mushroom traditionally used for focus. Early human trials have looked at memory and thinking in older adults.
Good to know: research used much larger amounts (grams per day). Here it's part of a daily mushroom blend.
Cordyceps
25 mgA mushroom used for generations for stamina. Small studies have looked at exercise performance.
Maitake
25 mgA culinary mushroom (hen of the woods) with naturally occurring beta-glucans.
Research
Shiitake
20 mgThe mushroom you know from dinner, included for everyday wellness.
Research
Biotin
5000 mcgA B vitamin your body uses to maintain normal hair, skin and nails.
Good to know: high-dose biotin can affect some lab tests. Tell your doctor you take it before blood work.
Folate (B9)
400 mcg DFEAn essential B vitamin your body needs to make new cells.
Vitamin D3
20 mcgThe sunshine vitamin. 20 mcg is 100% of the daily value for adults.
Melatonin
1 mgThe hormone your body makes to signal it's time to sleep. Studies look at how quickly people fall asleep. 1 mg is a gentle dose.
Valerian root
50 mgA traditional bedtime herb, studied for sleep quality with mixed results.
Lavender
20 mgThe calming classic, studied mostly for relaxation.
Research
Chamomile
10 mgThe bedtime-tea flower, studied for calm and sleep.
Research library
Read it yourself
The studies and official fact sheets behind our ingredients, in one place.
Orally disintegrating films: a modern expansion in drug delivery system
Irfan et al., Saudi Pharmaceutical Journal, 2016
Read →Advances in oral transmucosal drug delivery
Patel et al., Journal of Controlled Release, 2011
Read →The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness
Giesbrecht et al., Nutritional Neuroscience, 2010
Read →The combined effects of L-theanine and caffeine on cognitive performance and mood
Owen et al., Nutritional Neuroscience, 2008
Read →The effects of L-theanine, caffeine and their combination on cognition and mood
Haskell et al., Biological Psychology, 2008
Read →Effects of L-theanine on stress-related symptoms and cognitive functions in healthy adults
Hidese et al., Nutrients, 2019
Read →Acute effects of L-theanine, caffeine and EGCG on cognitive function and mood
Camfield et al., Nutrition Reviews, 2014
Read →The cognitive-enhancing outcomes of caffeine and L-theanine
Anas Sohail et al., Cureus, 2021
Read →Effects of tea or its compounds L-theanine and L-theanine plus caffeine on cognition
Payne et al., Nutrition Reviews, 2025
Read →Vitamin B12: fact sheet for health professionals
NIH Office of Dietary Supplements
Read →Improving effects of the mushroom Yamabushitake (lion's mane) on mild cognitive impairment
Mori et al., Phytotherapy Research, 2009
Read →Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects
Chen et al., Journal of Alternative and Complementary Medicine, 2010
Read →Mushrooms: what you need to know
NIH National Center for Complementary and Integrative Health
Read →A review of the use of biotin for hair loss
Patel et al., Skin Appendage Disorders, 2017
Read →Treatment of brittle fingernails with biotin: scanning electron microscopy
Colombo et al., Journal of the American Academy of Dermatology, 1990
Read →Brittle nails: response to daily biotin supplementation
Hochman et al., Cutis, 1993
Read →Biotin: fact sheet for health professionals
NIH Office of Dietary Supplements
Read →Folate: fact sheet for health professionals
NIH Office of Dietary Supplements
Read →Vitamin D: fact sheet for health professionals
NIH Office of Dietary Supplements
Read →Meta-analysis: melatonin for the treatment of primary sleep disorders
Ferracioli-Oda et al., PLoS One, 2013
Read →Valerian for sleep: a systematic review and meta-analysis
Bent et al., American Journal of Medicine, 2006
Read →Therapeutic efficacy and safety of chamomile for state anxiety, generalized anxiety disorder, insomnia, and sleep quality
Hieu et al., Phytotherapy Research, 2019
Read →The absolute bioavailability of oral melatonin
DeMuro et al., Journal of Clinical Pharmacology, 2000
Read →Valerian root in treating sleep problems: a systematic review and meta-analysis
Shinjyo et al., Journal of Evidence-Based Integrative Medicine, 2020
Read →Effects of valerian on sleep quality, depression and anxiety in hemodialysis patients
Tammadon et al., Oman Medical Journal, 2021
Read →Melatonin: what you need to know
NIH National Center for Complementary and Integrative Health
Read →Lavender
NIH National Center for Complementary and Integrative Health
Read →Chamomile
NIH National Center for Complementary and Integrative Health
Read →Quality
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SHOP THE MOODS*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The research linked here studies individual ingredients, often at different doses than in DOSIS, and is shared for education. Talk to your doctor before taking supplements if you're pregnant, nursing, take medication or have a medical condition.